Glomerular diseases are a group of conditions that damage the glomeruli, the tiny filtering units inside the kidneys. When these filters are affected, the kidneys cannot properly remove waste and excess fluids from the blood, leading to protein or blood in the urine and gradual loss of kidney function. Early diagnosis and specialized nephrology care are essential to prevent permanent kidney damage.
Glomerular diseases may be acute or chronic and include:
Glomerulonephritis
Nephrotic syndrome
IgA nephropathy
Lupus nephritis
Post-infectious glomerulonephritis
Vasculitis-related kidney disease
Each condition requires targeted evaluation and treatment.
Glomerular diseases can occur due to:
Autoimmune disorders
Infections
Diabetes and hypertension
Genetic factors
Certain medications
Systemic inflammatory diseases
Symptoms may vary depending on severity but commonly include:
Swelling of face, legs, or ankles
Foamy urine due to protein loss
Blood in urine
Reduced urine output
High blood pressure
Fatigue and weakness
Accurate diagnosis is crucial and may include:
Blood tests and urine analysis
Kidney function tests
Immunological tests
Ultrasound or imaging studies
Kidney biopsy for definitive diagnosis
Treatment depends on the type and severity of the disease and may include:
Immunosuppressive or steroid therapy
Blood pressure control
Medications to reduce protein loss in urine
Dietary modifications
Management of fluid and electrolyte balance
Early treatment helps preserve kidney function.
Glomerular diseases often require:
Regular kidney function monitoring
Ongoing medication adjustments
Prevention of disease relapse
Monitoring for progression to chronic kidney disease
Consult a kidney specialist if you have:
Persistent swelling or foamy urine
Blood in urine
Abnormal kidney test results
Uncontrolled blood pressure
Known autoimmune disease with kidney involvement
Expertise in complex kidney disorders
Accurate diagnosis with biopsy guidance
Personalized treatment plans
Long-term monitoring and patient education